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New Issue Published Current Topic Medicinal Chemistry Vol. 17 Issue 8
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Sunday, January 29, 2017
Wednesday, January 25, 2017
Wednesday, January 18, 2017
Sunday, January 15, 2017
Tuesday, January 3, 2017
Most Accessed Article: Multivariate Analysis of Magnetic Resonance Imaging Signals of the Human Brain
Most Accessed Article: Multivariate Analysis of Magnetic Resonance Imaging Signals of the Human Brain
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Highlighted Article:The Glitter of Carbon Nanostructures in Hybrid/Composite Hydrogels for Medicinal Use
Highlighted Article:The Glitter of Carbon Nanostructures in Hybrid/Composite Hydrogels for Medicinal Use
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Most Cited Article: Prospects for Developing New Antibacterials Targeting Bacterial Type IIA Topoisomerases
Most Cited Article: Prospects for Developing New Antibacterials Targeting Bacterial Type IIA Topoisomerases
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Models of In-Vivo Bacterial Infections for the Development of Antimicrobial Peptide-based Drugs
Models of In-Vivo Bacterial Infections for the Development of Antimicrobial Peptide-based Drugs
[ Vol. 17 , Issue. 5 ]
Author(s):
Jlenia Brunetti, Chiara Falciani, Luisa Bracci and Alessandro Pini Pages 613 - 619 ( 7 )
Abstract:
The increasing frequency of multi-resistant Gram-positive and Gram-negative bacteria and a long-term decreasing trend in the development of new antimicrobial molecules prompts research for new anti-infective...
Antimicrobial Peptides as a Strategy to Combat Fungal Biofilms
Antimicrobial Peptides as a Strategy to Combat Fungal Biofilms
[ Vol. 17 , Issue. 5 ]
Author(s):
Nicolas Delattin, Katrijn De Brucker, Kaat De Cremer, Bruno P.A. Cammue and Karin Thevissen Pages 604 - 612 ( 9 )
Abstract:
Invasive fungal infections caused by opportunistic fungal pathogens are associated with high mortality rates, mainly due to the occurrence of genotypic and/or phenotypic resistance. One of the causes of phenotypic resistance...
Antimicrobial Peptides as Anti-biofilm Agents in Medical Implants
Antimicrobial Peptides as Anti-biofilm Agents in Medical Implants
[ Vol. 17 , Issue. 5 ]
Author(s):
Susana Sánchez-Gómez and Guillermo Martínez-de-Tejada Pages 590 - 603 ( 14 )
Abstract:
Biofilm-associated infections constitute a daunting threat to human health, since these pathologies increase patient mortality and morbidity, resulting in prolonged hospitalization periods and heavy economic losses. Moreover, these infections contribute...
Mimics of Host Defense Proteins; Strategies for Translation to Therapeutic Applications
Mimics of Host Defense Proteins; Strategies for Translation to Therapeutic Applications
[ Vol. 17 , Issue. 5 ]
Author(s):
Richard W. Scott and Gregory N. Tew Pages 576 - 589 ( 14 )
Abstract:
New infection treatments are urgently needed to combat the rising threat of multi-drug resistant bacteria. Despite early clinical set-backs attention has re-focused on host defense proteins (HDPs), as potential sources for new and effective antimicrobial...
The Medical Potential of Antimicrobial Peptides from Insects
The Medical Potential of Antimicrobial Peptides from Insects
[ Vol. 17 , Issue. 5 ]
Author(s):
Miray Tonk and Andreas Vilcinskas Pages 554 - 575 ( 22 )
Abstract:
Antimicrobial peptides (AMPs) are peptide-based effector molecules produced by the innate immune system to combat microbes. Insects produce the broadest repertoire of AMPs, and their potent antimicrobial activity in vitro and in vivo has promoted their development as alternatives...
Use of Peptide Libraries for Identification and Optimization of Novel Antimicrobial Peptides
Use of Peptide Libraries for Identification and Optimization of Novel Antimicrobial Peptides
[ Vol. 17 , Issue. 5 ]
Author(s):
Martin Ashby, Asya Petkova, Jurnorain Gani, Ralf Mikut and Kai Hilpert Pages 537 - 553 ( 17 )
Abstract:
The increasing rates of resistance among bacteria and to a lesser extent fungi have resulted in an urgent need to find new molecules that hold therapeutic promise against multidrug-resistant strains. Antimicrobial...
Elucidating Unusual Modes of Action and Resistance of Antibacterial Peptides
Elucidating Unusual Modes of Action and Resistance of Antibacterial Peptides
[ Vol. 17 , Issue. 5 ]
Author(s):
Leandro dos Santos Machado, Esther Vilas Boas de Carvalho, Flávia Varela de Affonseca e Silva, Pedro Vinícius Dos Santos Cabreira and Octavio Luiz Franco Pages 520 - 536 ( 17 )
Abstract:
The emergence of bacterial resistance to conventional antibiotics has been become a major issue in the health system. Currently, studies are...
Membrane-active Antimicrobial Peptides as Template Structures for Novel Antibiotic Agents
Membrane-active Antimicrobial Peptides as Template Structures for Novel Antibiotic Agents
[ Vol. 17 , Issue. 5 ]
Author(s):
Karl Lohner Pages 508 - 519 ( 12 )
Abstract:
The increase of pathogens being resistant to antibiotics represents a global health problem and therefore it is a pressing need to develop antibiotics with novel mechanisms of action. Host defense peptides, which have direct antimicrobial activity (also termed antimicrobial...
Editorial (Thematic Issue : Antimicrobial Peptides)
Editorial (Thematic Issue : Antimicrobial Peptides)
[ Vol. 17 , Issue. 5 ]
Author(s):
Malgorzata Dawgul Pages 507 - 507 ( 1 )
Editorial, (Thematic, Issue, :, Antimicrobial, Peptides)
Affiliation:
Department of Inorganic Chemistry Faculty of Pharmacy Medical University of Gdansk, Gdansk Poland.
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